Polynucleotides, also called PN or PDRN are an injectable, skin-boosting, regenerative treatment that has gained popularity in recent years. Although, they have been used in medicine since the 1980’s to treat joint issues.

Polynucleotides are made up of chains of nucleotides, which are the building blocks of DNA and RNA. When used in aesthetics, polynucleotides are typically derived from the sperm of salmon or trout, and are then purified and sterilised for medical use. They are then injected into the skin to provide instant hydration and long term bio-remodelling.

Polynucleotides have several skin-boosting benefits for the skin, including improving skin texture and elasticity and reducing fine lines and wrinkles. They do this by providing instant hydration whilst also promoting fibroblast proliferation and collagen synthesis. They are also thought to have anti-inflammatory and wound-healing properties, which can help to reduce redness, swelling, and other signs of skin damage.